Art and Science of Laboratory Medicine. Clinical laboratory and biomedical science related news, abstracts and images for medical laboratory professionals, students and other laboratory geeks.
Art and Science of Laboratory Medicine
Saturday, September 7, 2013
Homozygous hemoglobin C disease
A 44-year-old African American female presented with a pain crisis and a history of hemoglobinopathy, menometrorrhagia secondary to acquired von Willebrand factor (vWF) deficiency, and a history of multiple vaso-occlusive events necessitating lifelong warfarin therapy. Further history revealed that she had four pain crises in the previous year requiring hospitalizations, multiple splenic infarcts with resultant autosplenectomy, one normal pregnancy with no preceding miscarriages, and no history of bone necrosis.